PTEN isoforms with dual and opposing function

compactifications and function spaces on weighted semigruops

chapter one is devoted to a moderate discussion on preliminaries, according to our requirements. chapter two which is based on our work in (24) is devoted introducting weighted semigroups (s, w), and studying some famous function spaces on them, especially the relations between go (s, w) and other function speces are invesigated. in fact this chapter is a complement to (32). one of the main fea...

Welding Aluminum Alloy 6061 with Opposing Dual Torch Gtaw Process

Cracking is a major concern in welding aluminum alloys. Although weld solidification cracks can be eliminated through addition of filler alloy, the additives modify the alloy or base-metal constituents and may not always be desirable. High-energy beam processes, such as electron-beam welding, that result in minimal heat input reduce crack sensitivity, but their high cost limits their applicatio...

SynGAP isoforms exert opposing effects on synaptic strength

Alternative promoter usage and alternative splicing enable diversification of the transcriptome. Here we demonstrate that the function of Synaptic GTPase-Activating Protein (SynGAP), a key synaptic protein, is determined by the combination of its amino-terminal sequence with its carboxy-terminal sequence. 5' rapid amplification of cDNA ends and primer extension show that different N-terminal pr...

Two isoforms of tissue transglutaminase mediate opposing cellular fates.

Opposing cellular responses are typically regulated by distinct sets of genes. However, tissue transglutaminase (TGase) provides an interesting example of a single gene product that has been implicated both in affording protection against cellular insults as well as in promoting cell death. Here, we shed some light on how these conflicting activities might be manifested by demonstrating that al...

Immunoregulatory Functions during Isoforms of Vitamin E Have Opposing